The Cannabinoid system consists of cannabinoids and Cannabinoid receptors. cannabinoids can be subdivided into endocannabinoids, (produced by your own body, such as anandamide), plant cannabinoids (produced by cannabis plants, such as THC) and synthetic cannabinoids (produced by industry, such as Marinol).
cannabinoids are lipid/fatty compounds, which are very poorly solvable in water but can easily migrate through fat/lipids such as cell membranes.
Cannabinoid receptors are a diverse group of proteins that bind cannabinoids and convey their message. Most Cannabinoid receptors are G protein-coupled receptors (see GPCR introduction), which means that the effect of their activation is highly variable and can be modulated in many ways.
In this section we will try to introduce each component of the Cannabinoid system in a way that is both easy to understand and scientifically correct. We will give a brief general description of its characteristics, followed by a more complete scientific description of its synthesis, degradation, distribution and interactions and reference material.
Each entry is fully hyperlinked to their relevant partners so clicking through this section should give a fairly intuitive grasp of the web of interactions within the Cannabinoid system. This forms the background against which the therapeutic properties of cannabinoids are discussed in a whole range of disorders.
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