K-ATP is a potassium channel that is sensitive to ATP and therefore to cellular energy levels. K-ATP functions to control cellular energy levels. K-ATP is not a classic cannabinoid receptor but its activity is modulated by cannabinoids. Since cannabinoids have a physiological effect on K-ATP it is effectively a cannabinoid receptor.

Chemical Name: 
ATP-sensitive potassium channel
IUPHAR entry: 
Wikipedia entry: 
Distribution: 

K-ATP is present on both plasma- and intracellular membranes.

Endocannabinoids: 
Literature Discussion: 

Anandamide  

References:

Pertwee, R.G., Howlett, A.C., Abood, M.E., Alexander, S.P.H., Di Marzo, V., Elphick, M.R., Greasley, P.J., Hansen, H.S., Kunos, G., Mackie, K., et al. (2010). International Union of Basic and Clinical Pharmacology. LXXIX. cannabinoid receptors and their ligands: beyond CB₁ and CB₂. Pharmacol. Rev. 62, 588–631.

Tags: 

Anandamide

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