10β-OH-Δ8-THC

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Introduction

10β-OH-Δ8-THC has been recently identified in the cannabis plant. It has therapeutic properties as antinociceptive and hypothermic effects, but more research is needed.

Chemical Name

10β-hydroxy-Δ8-tetrahydrocannabinol

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Literature Discussion

10β-OH-Δ8-THC binds to CB1 and CB2 and showed antinociceptive and hypothermic actions in doses of 40 mg/kg (Radwan et al., 2015)

References:

Radwan, M. M., ElSohly, M. A., El-Alfy, A. T., Ahmed, S. A., Slade, D., Husni, A. S., … Ross, S. A. (2015). Isolation and Pharmacological Evaluation of Minor cannabinoids from High-Potency Cannabis sativa. Journal of natural products, 78(6), 1271-1276. https://doi.org/10.1021/acs.jnatprod.5b00065