Cav2.2

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Introduction

Cav2.2 is a calcium channel of the N-type that is involved in many basal brain processes including learning and memory. Cav2.2 is not a classic Cannabinoid receptor but its activity is modulated by cannabinoids. Since cannabinoids have a physiological effect on Cav2.2 it is effectively a Cannabinoid receptor.

Chemical Name

Cav2.2, N-type calcium channel

IUPHAR entry

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Literature Discussion

Anandamide  

References:

Pertwee, R.G., Howlett, A.C., Abood, M.E., Alexander, S.P.H., Di Marzo, V., Elphick, M.R., Greasley, P.J., Hansen, H.S., Kunos, G., Mackie, K., et al. (2010). International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂. Pharmacol. Rev. 62, 588–631.

Distribution from Human Protein Atlas: 
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