cannabinoids have excellent therapeutic potential for the treatment of epilepsy. In the brain, the endocannabinoid system tends to keep neuronal activity wihtin acceptable boundaries.


Cav2.2 is a calcium channel of the N-type that is involved in many basal brain processes including learning and memory. Cav2.2 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids. Since cannabinoids have a physiological effect on Cav2.2 it is effectively a cannabinoid receptor.