Cav3.1 is a calcium channel of the T-type that is involved in many processes in the brain and other tissues. Contrary to other calcium channels Cav3.1 is activated by relatively low/negative voltages. Cav3.1 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids. Since cannabinoids have a physiological effect on Cav3.1 it is effectively a cannabinoid receptor.

Chemical Name: 
Calcium channel, voltage-dependent, T type, alpha 1G subunit
IUPHAR entry: 
Wikipedia entry: 

Brain > ovary > placenta. Cerebellum > thalamus > neocortex > substantia nigra > medulla > striatum.

Literature Discussion: 

NarGly NADA Anandamide CBD Δ9THC  


Pertwee, R.G., Howlett, A.C., Abood, M.E., Alexander, S.P.H., Di Marzo, V., Elphick, M.R., Greasley, P.J., Hansen, H.S., Kunos, G., Mackie, K., et al. (2010). International Union of Basic and Clinical Pharmacology. LXXIX. cannabinoid receptors and their ligands: beyond CB₁ and CB₂. Pharmacol. Rev. 62, 588–631.