Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Nav1.2 is a sodium channel that is involved in action potential generation in neurons and in muscle. Nav1.2 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Kv4.3 is a potassium channel that is involved in the repolarisation of action potentials in cardiac muscle. Kv4.3 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Kv3.1 is a potassium channel that functions in action potential repolarisation in fast-firing neurons. Kv3.1 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Kv1.5 is a potassium channel that is involved in restoring the resting membrane potential after depolarisation. Kv1.5 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Kv1.2 is a potassium channel that is responsible for maintaining resting membrane potential and regulating excitability in neurons. Kv1.2 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
GPR18 is involved in apoptosis, microglial migration in the CNS and other immune responses.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
CB2 is primarily expressed in the immune cells and tissues of the body. Like CB1, CB2 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently lowers cAMP upon activation. This, in turn, regulates many second messenger pathways.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Cav3.2 is a calcium channel of the T-type that is involved in many processes in the brain and other tissues. Contrary to other calcium channels Cav3.2 is activated by relatively low/negative voltages.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Cav2.2 is a calcium channel of the N-type that is involved in many basal brain processes including learning and memory. Cav2.2 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids. Since cannabinoids have a physiological effect on Cav2.2 it is effectively a cannabinoid receptor.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Cav2.1 is a calcium channel of the P/Q type that is central to many brain processes, including learning and memory. Cav2.1 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids.