PEA

Suspected endocannabinoid.

Stroke

A stroke is marked by reduced blood flow to the brain. This reduction can be due to a blocked blood vessle (ischaemia) or a ruptured blood vessle (aneurism). Either way, as a result (part of) the brain is deprived of oxygen and nutrients which in turn causes neuronal degradation and cognitive decline.

Parkinson's

Parkinson's Disease is a degenerative disorder of the nervous system marked by accelerated degeneration of dopamine-producing neurons in the Substantia Nigra in the brain.

Typical symptoms of Parkinson's Disease , such as (intentional) tremor, rigidity and slowness of movement are mostly ascribed to degenerating Substantia Nigra neurons.

Pain

Pain is a very good target for therapeutic cannabinoids. Many endocannabinoids, plant cannabinoids and cannabinoid receptors have been linked to pain management or analgesia.

Obesity

Energy homeostasis (balance)  is one of the primary functions of the endocannabinoid system.

Multiple Sclerosis

Multiple Sclerosis is one of the diseases where a therapeutic role for cannabinoids has been investigated for a long time.

Hypoxic-ischemic encephalopathy

Hypoxic-ischemic encephalopathy is a form of brain injury caused by oxygen deprivation during the birth process. It can cause sensorimotor and cognitive impairments including physical and intellectual disability. The endocannabinoid system can regulate the underlying processes of hypoxic-ischemic encephalopathy when its occurring, therefore cannabinoids could help to ameliorate the symptoms related to it.

Eczema

Eczema or dermatitis is a (chronic) inflammation of the skin. Eczema is marked by itchy skin and crusty skin lesions. It is not known what exactly causes eczema but an over-active immune system may at least be part of the cause. Therefore, a faulty endocannabinoid system may cause eczema offering potential for cannabinoid-based therapy.

Cystitis

Cystitis is an infection of the urinary tract.

Bulimia

cannabinoids and endocannabinoids are known to strongly affect eating behavior. THC typically induces hunger and THCV suppresses it.