Parkinson's

Parkinson's Disease is a degenerative disorder of the nervous system marked by accelerated degeneration of dopamine-producing neurons in the Substantia Nigra in the brain.

Typical symptoms of Parkinson's Disease , such as (intentional) tremor, rigidity and slowness of movement are mostly ascribed to degenerating Substantia Nigra neurons.

Pain

pain is a very good target for therapeutic cannabinoids.

PPARγ

pparγ is part of the nuclear receptor family and one of the non-GPCR cannabinoid receptors. pparγ is involved in the regulation of fat cells/adipose tissue, insulin sensitivity and inflammation.

GPR119

GPR119 is involved in insulin secretion and its activation was shown to reduce food intake, suggesting a metabolic function.