CB1 is the main cannabinoid receptor in the brain but is also found in other tissues. CB1 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently reduces cAMP upon activation. This in turn regulates many second messenger pathways. 

pparγ is part of the nuclear receptor family and one of the non-GPCR cannabinoid receptors. pparγ is involved in the regulation of fat cells/adipose tissue, insulin sensitivity and inflammation.

Suspected endocannabinoid.