Bladder cancer

Bladder cancers develop from the epithelial lining of the urinary bladder. cannabinoid receptors in the human bladder cancer cells could be targeted to treat the disease, but more research is needed in this field.

Psoriasis

Psoriasis is an auto-immune disease characterized by itchy skin lesions. Psoriasis arises when the immune system mistakenly identifies skin cells as foreign matter and causes over-production of new skin cells.

Prostate Cancer

Prostate cancer is the development of cancer in the prostate.

Parkinson's

Parkinson's Disease is a degenerative disorder of the nervous system marked by accelerated degeneration of dopamine-producing neurons in the Substantia Nigra in the brain.

Typical symptoms of Parkinson's Disease , such as (intentional) tremor, rigidity and slowness of movement are mostly ascribed to degenerating Substantia Nigra neurons.

Multiple Sclerosis

Multiple Sclerosis is one of the diseases where a therapeutic role for cannabinoids has been investigated for a long time.

Leukemia

Leukemia cancers usually begin in the bone marrow and involves abnormal white blood cell production. Leukemia has been reported to be sensitive to the effects of cannabinoids THC and CBD. These cannabinoids can be used to treat leukemia.

Huntington's

Huntington's disease is a genetic neurodegenerative disorder, marked by preferential degeneration of neurons in the basal ganglia (caudate and putamen) and accompanied by motor deficits, cognitive impairment and psychiatric symptoms. There is considerable evidence for the involvement of the endocannabinoid system in Huntington's but clinical trials so far have been inconclusive.

AIDS

The Acquired Immune Deficiency Syndrome is caused by the Human Immunodeficiency Virus. HIV/AIDS attacks cells of the immune system making the body more susceptible to infections and tumors. As a result, patients often suffer from nausea, loss of appetite, intractable pain and other secondary symptoms often associated with cancer (cachexia/wasting syndrome).

Glioblastoma

Glioblastoma is a malignant brain tumor originated in brain cells called astrocytes. Glioblastoma is one of the most promising targets for cannabinoid therapy. Several research groups found anti-tumor properties of cannabinoids in vitro and in vivo studies.

Epilepsy

cannabinoids have excellent therapeutic potential in epilepsy. In the brain, cannabinoids tend to keep neuronal activity wihtin acceptable boundaries. More importantly, cannabinoids prevent hypersynchronisation of cortical neurons (which is the very definition of a seizure).