α2r

α2 receptors are classically known as adrenalin receptors. However, α2 receptors also bind CBG at very high affinity and are therefore also cannabinoid receptors. The interaction between CBG and α2 receptors may be relevant in the treatment of pain and depression, but more research is required.

TRPM8

TRPM8 is involved in sensory perception.

TRPA1

TRPA1 is best known as a sensor for environmental irritants, pain, cold and stretch.

CB2

CB2 is primarily expressed in the immune cells and tissues of the body. Like CB1, CB2 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently lowers cAMP upon activation. This, in turn, regulates many second messenger pathways.

4-OH-5-acetoxy-CBG

4-OH-5-acetoxy-CBG is a recently discovered cannabinoid. The physiological and therapeutic properties of 4-OH-5-acetoxy-CBG remain to be investigated.

5-metoxy-CBG

5-metoxy-CBG is a recently discovered cannabinoid. The physiological and therapeutic properties of 6,7-epoxy-CBG remain to be investigated.

6,7-epoxy-CBG

6,7-epoxy-CBG is a recently discovered cannabinoid. The physiological and therapeutic properties of 6,7-epoxy-CBG remain to be investigated.

CBGV

CBGV interacts with several receptors and may have anti-inflammatory and analgesic properties but this is still under investigation.

CBGA

CBGA is a precursor for the production of THC but has some therapeutic, anti-inflammatory, value as well. Given the number of receptor interactions CBGA is likely to have more therapeutic properties.

Olivetolic acid

Olivetolic acid is a cannabinoid precursor from which THC and its metabolites are made. To date, no interesting biological or therapeutic functions have been described for Olivetolic acid.