Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Glioblastoma is a malignant brain tumor originated in brain cells called astrocytes. Glioblastoma is one of the most promising targets for cannabinoid therapy. Several research groups found anti-tumor properties of cannabinoids in vitro and in vivo studies.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
leukemia cancers usually begin in the bone marrow and involves abnormal white blood cell production.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
cannabinoids have excellent therapeutic potential for the treatment of epilepsy. In the brain, the endocannabinoid system tends to keep neuronal activity wihtin acceptable boundaries.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
arthritis is marked by painful inflammation of one or more joints.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
TRPV3 is one of the non-GPCR-coupled cannabinoid receptors. TRPs are typically involved in pain sensation.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
TRPV1 is part of the transient receptor potential family and is one of the non-GPCR cannabinoid receptors. TRPV1 is involved in thermoregulation and pain detection (nociception).
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
CB2 is primarily expressed in the immune cells and tissues of the body. Like CB1, CB2 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently lowers cAMP upon activation. This, in turn, regulates many second messenger pathways.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Docosahexaenoylethanolamine is an endocannabinoid that is synthesized from docosahexaenoic acid / DHA, the major omega-3 fatty acid in the brain.