Glioblastoma

Glioblastoma is a malignant brain tumor originated in brain cells called astrocytes. Glioblastoma is one of the most promising targets for cannabinoid therapy. Several research groups found anti-tumor properties of cannabinoids in vitro and in vivo studies.

Leukemia

leukemia cancers usually begin in the bone marrow and involves abnormal white blood cell production.

Prostate Cancer

Prostate cancer is the development of cancer in the prostate.

Epilepsy

cannabinoids have excellent therapeutic potential for the treatment of epilepsy. In the brain, the endocannabinoid system tends to keep neuronal activity wihtin acceptable boundaries.

Arthritis

arthritis is marked by painful inflammation of one or more joints.

Pain

pain is a very good target for therapeutic cannabinoids.

TRPV3

TRPV3 is one of the non-GPCR-coupled cannabinoid receptors. TRPs are typically involved in pain sensation.

TRPV1

TRPV1 is part of the transient receptor potential family and is one of the non-GPCR cannabinoid receptors. TRPV1 is involved in thermoregulation and pain detection (nociception).

CB2

CB2 is primarily expressed in the immune cells and tissues of the body. Like CB1, CB2 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently lowers cAMP upon activation. This, in turn, regulates many second messenger pathways.

DHEA

Docosahexaenoylethanolamine is an endocannabinoid that is synthesized from docosahexaenoic acid / DHA, the major omega-3 fatty acid in the brain.