THCP

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Introduction

THCP is a phytocannabinoid analogous to THCTHCP have similar interactions with CB1 and CB2 compared to THC, and its effects are probably similar but more potent compared to THC.

 

Chemical Name

(-)-trans-Δ9-tetrahydrocannabiphorol

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Literature Discussion

THCP and CBDP have been identified in the italian medical cannabis strain FM2. THCP binds to both CB1 and CB2 receptors, with around 30 times higher affinity than THC. THCP causes effects similar to THC when it was administered to animals (Citti et al., 2019).

 

References

Citti, C., Linciano, P., Russo, F., Luongo, L., Iannotta, M., Maione, S., Laganà, A., Capriotti, A. L., Forni, F., Vandelli, M. A., Gigli, G., & Cannazza, G. (2019). A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ9-tetrahydrocannabinol: Δ9-Tetrahydrocannabiphorol. Scientific Reports, 9. https://doi.org/10.1038/s41598-019-56785-1

Distribution from Human Protein Atlas: