Insomnia is a sleep disorder characterized by inability to sleep or sleeping less time than desired. The endocannabinoid system plays a role in sleep processes and medical cannabis users already reported benefits of cannabis use to sleep. More research on the molecular mechanism of cannabinoids in sleep processes could uncover their potential on treating sleep disorders.

Addiction is a complex physiological phenomenon that is intimately linked to the dopamine neurotransmitter system. Neurons in the dopamine system are studded with cannabinoid receptors (like CB1) which explains the addictive properties of cannabinoid substances. However, the interaction between the cannabinoid system and the dopamine system also offers opportunities for cannabinoids in the treatment of addiction to for instance alcohol, food, nicotine or opioids.

Autism is a neurodevelopmental disorder characterized by impaired social interaction, verbal and non-verbal communication, and restricted and repetitive behavior.

cannabinoids and endocannabinoids are known to strongly affect eating behavior. THC typically induces hunger and THCV suppresses it.

Cystitis is an infection of the urinary tract.

Both plant cannabinoids and the endocannabinoid system have been implicated as risk factors in the development of depression as well as therapeutic targets to treat depression.

Diabetes has two major forms: Type 1 Diabetes is an auto-immune disorder where insulin-producing β-cells in the pancreatic Islets of Langerhans are attacked by the body's immune system resulting in reduced insulin production.

Migraine is a chronic neurological disorder that is mostly characterized by severe headaches and aura.

Malaria is an infectious disease caused by Plasmodia parasitic protozoa. This disease is transmitted by a mosquito bite with a large variety of symptoms like fever, headache and seizures. It can cause neurological problems and death. For those people who survive Malaria infection, the chances to have neurological complications and cognitive impairments are high.