2AG

2AG is a major endocannabinoid produced from lipids in cellular membranes, mostly but not exclusively in response to cellular activity.

TRPV1

TRPV1 is part of the transient receptor potential family and is one of the non-GPCR cannabinoid receptors. TRPV1 is involved in thermoregulation and pain detection (nociception).

Epilepsy

cannabinoids have excellent therapeutic potential in Epilepsy. In the brain, cannabinoids tend to keep neuronal activity wihtin acceptable boundaries.

Cav3.1

Cav3.1 is a calcium channel of the T-type that is involved in many processes in the brain and other tissues. Contrary to other calcium channels Cav3.1 is activated by relatively low/negative voltages.

Diabetes

Diabetes has two major forms: Type 1 Diabetes is an auto-immune disorder where insulin-producing β-cells in the pancreatic Islets of Langerhans are attacked by the body's immune system resulting in reduced insulin production.

Depression

Both plant cannabinoids and the endocannabinoid system have been implicated as risk factors in the development of Depression as well as therapeutic targets to treat Depression.

Cystitis

Cystitis is an infection of the urinary tract.

COPD

COPD is a chronic lung disease. To date, no cure exists for COPD and therefore most treatments focus on reducing symptoms and suppressing discomfort.

Bulimia

cannabinoids and Endocannabinoids are known to strongly affect eating behavior. THC typically induces hunger and THCV suppresses it.

Bone cancer

Bone cancers result from primary tumor invasion to bone. cannabinoids can be used to relieve Bone Cancer pain through their anti-inflammatory properties and also they could be used to treat cancer itself.