Inflammation

Balancing inflammation is one of the primary functions of the endocannabinoid system and research shows the involvement of several endocannabinoids and their synthesizig and degrading enzymes in the regulation of inflammation suggesting a therapeutic role for plant cannabinoids.

Crohn's Disease

Crohn's disease is a chronic inflammatory bowel disease (IBD). It affects any part of the gastrointestinal tract with symptoms like abdominal pain, diarrhea, weight loss, skin rushes or fever. The causes of the disease are not well known, but genetics and environment play an important role on it.

Functional Gastro-Intestinal Disorders

Functional Gastro-Intestinal Disorders form a spectrum of disorders to the gastro-intestinal tract ranging from heartburn to diarrhea. Cannabis has been used for centuries to treat diseases such as diarrhea and research now shows a strong involvement of the endocannabinoid system in the function of the gastro-intestinal tract and the regulation of bowel movement.

Parkinson's

Parkinson's Disease is a degenerative disorder of the nervous system marked by accelerated degeneration of dopamine-producing neurons in the Substantia Nigra in the brain.

Typical symptoms of Parkinson's Disease , such as (intentional) tremor, rigidity and slowness of movement are mostly ascribed to degenerating Substantia Nigra neurons.

Alzheimer's disease

Alzheimer’s disease is a chronic neurodegenerative disease and the main cause of dementia. Main common symptoms of dementia are related with memory but other cognitive processes are affected during the development of the disease.

Stroke

A Stroke is marked by reduced blood flow to the brain. This reduction can be due to a blocked blood vessle (ischaemia) or a ruptured blood vessle (aneurism). Either way, as a result (part of) the brain is deprived of oxygen and nutrients which in turn causes neuronal degradation and cognitive decline.

Psoriasis

psoriasis is an auto-immune disease characterized by itchy skin lesions. psoriasis arises when the immune system mistakenly identifies skin cells as foreign matter and causes over-production of new skin cells.

Obesity

Energy homeostasis (balance)  is one of the primary functions of the endocannabinoid system.

Multiple Sclerosis

multiple sclerosis is one of the diseases where a therapeutic role for cannabinoids has been investigated for a long time.

Hypoxic-ischemic encephalopathy

Hypoxic-ischemic encephalopathy is a form of brain injury caused by oxygen deprivation during the birth process. It can cause sensorimotor and cognitive impairments including physical and intellectual disability.