Bladder cancer

Bladder cancers develop from the epithelial lining of the urinary bladder. cannabinoid receptors in the human Bladder Cancer cells could be targeted to treat the disease, but more research is needed in this field.

Diabetes

Diabetes has two major forms: Type 1 diabetes is an auto-immune disorder where insulin-producing β-cells in the pancreatic Islets of Langerhans are attacked by the body's immune system resulting in reduced insulin production. Type 2 diabetes results from increased tolerance of cells to insulin resulting in a reduced effect of insulin.

Alzheimer's disease

Alzheimer’s disease is a chronic neurodegenerative disease and the main cause of dementia. Main common symptoms of dementia are related with memory but other cognitive processes are affected during the development of the disease.

PPARγ

PPARγ is part of the nuclear receptor family and one of the non-GPCR cannabinoid receptors. PPARγ is involved in the regulation of fat cells/adipose tissue, insulin sensitivity and inflammation.

CB2

CB2 is primarily expressed in the immune cells and tissues of the body. Like CB1, CB2 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently lowers cAMP upon activation. This, in turn, regulates many second messenger pathways.

Huntington's

Huntington's disease is a genetic neurodegenerative disorder, marked by preferential degeneration of neurons in the basal ganglia (caudate and putamen) and accompanied by motor deficits, cognitive impairment and psychiatric symptoms. There is considerable evidence for the involvement of the endocannabinoid system in Huntington's but clinical trials so far have been inconclusive.

COPD

COPD is a chronic lung disease. To date, no cure exists for COPD and therefore most treatments focus on reducing symptoms and suppressing discomfort.

Cancer

Cancer treatment is one of the main therapeutic applications of cannabinoids. Research has identified cannabinoids with excellent analgesic properties, cannabinoids that increase appetite and cannabinoids that reduce nausea.

Prostate Cancer

Prostate cancer is the development of cancer in the prostate.

Cervical cancer

Cervical Cancer is a type of cancer that develops from the cervix.