CB1

CB1 is the main cannabinoid receptor in the brain but is also found in other tissues. CB1 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently reduces cAMP upon activation. This in turn regulates many second messenger pathways.

CBV

Cannabivarin/CBV is a non-psychoactive cannabinoid, analogous to cannabinol/CBN but with a shorter side-chain.

THCV

THCV is a phytocannabinoid analogous to THC.

Bulimia

cannabinoids and endocannabinoids are known to strongly affect eating behavior. THC typically induces hunger and THCV suppresses it.

Parkinson's

Parkinson's Disease is a degenerative disorder of the nervous system marked by accelerated degeneration of dopamine-producing neurons in the Substantia Nigra in the brain.

Typical symptoms of Parkinson's Disease , such as (intentional) tremor, rigidity and slowness of movement are mostly ascribed to degenerating Substantia Nigra neurons.

TRPV3

TRPV3 is one of the non-GPCR-coupled cannabinoid receptors. TRPs are typically involved in pain sensation.

TRPA1

TRPA1 is best known as a sensor for environmental irritants, pain, cold and stretch.

TRPM8

TRPM8 is involved in sensory perception.

OCD

OCD is an Anxiety disorder characterised by the obsessive urge for repetitive behaviour.

Obesity

Energy homeostasis (balance)  is one of the primary functions of the endocannabinoid system.