CBD

CBD is the second most common cannabinoid from the plant of cannabis.

CB1

CB1 is the main cannabinoid receptor in the brain but is also found in other tissues. CB1 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently reduces cAMP upon activation. This in turn regulates many second messenger pathways.

CBDV

CBDV is a non-psychoactive cannabinoid with anti-convulsant properties like its homolog CBD. It has also other potential therapeutic properties as antitumorigenic, anti-acne and antiemetic effects.

Glioblastoma

Glioblastoma is a malignant brain tumor originated in brain cells called astrocytes. Glioblastoma is one of the most promising targets for cannabinoid therapy.

TRPM8

TRPM8 is involved in sensory perception.

TRPA1

TRPA1 is best known as a sensor for environmental irritants, pain, cold and stretch.

TRPV3

TRPV3 is one of the non-GPCR-coupled cannabinoid receptors. TRPs are typically involved in pain sensation.

Epilepsy

cannabinoids have excellent therapeutic potential in Epilepsy. In the brain, cannabinoids tend to keep neuronal activity wihtin acceptable boundaries.

Cav3.3

Cav3.3 is a calcium channel of the T-type that is involved in many brain processes. Contrary to other calcium channels Cav3.3 is activated by relatively low/negative voltages.

Cav3.2

Cav3.2 is a calcium channel of the T-type that is involved in many processes in the brain and other tissues. Contrary to other calcium channels Cav3.2 is activated by relatively low/negative voltages.