Submitted by Alberto on Tue, 05/30/2017 - 14:14
CB1 is the main Cannabinoid receptor in the brain but is also found in other tissues. CB1 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently reduces cAMP upon activation. This in turn regulates many second messenger pathways.
Submitted by Alberto on Tue, 05/30/2017 - 11:35
2AG is a major
endocannabinoid produced from lipids in cellular membranes, mostly but not exclusively in response to cellular activity.
Submitted by Alberto on Tue, 05/30/2017 - 11:14
Anandamide was the first identified endocannabinoid, named after the Sanskrit 'ananda' for inner bliss. Anandamide is produced from lipids in cellular membranes throughout the body.
Submitted by admin on Mon, 03/14/2016 - 13:14
Glycine receptors are sensitive to Glycine and produce a hyperpolarising current upon activation. GlyRs are not classic Cannabinoid receptora but their activity is modulated by cannabinoids.
Submitted by admin on Mon, 03/14/2016 - 13:14
Submitted by admin on Mon, 03/14/2016 - 13:14
Submitted by admin on Mon, 03/14/2016 - 13:14
Bone cancers result from primary tumor invasion to bone. cannabinoids can be used to relieve Bone Cancer pain through their anti-inflammatory properties and also they could be used to treat cancer itself.
Submitted by admin on Mon, 03/14/2016 - 13:14
Parkinson's Disease is a degenerative disorder of the nervous system marked by accelerated degeneration of dopamine-producing neurons in the Substantia Nigra in the brain.
Typical symptoms of Parkinson's Disease , such as (intentional) tremor, rigidity and slowness of movement are mostly ascribed to degenerating Substantia Nigra neurons.
Submitted by admin on Mon, 03/14/2016 - 13:14
Alzheimer’s disease is a chronic neurodegenerative disease and the main cause of dementia. Main common symptoms of dementia are related with memory but other cognitive processes are affected during the development of the disease.
Submitted by admin on Mon, 03/14/2016 - 13:14
A Stroke is marked by reduced blood flow to the brain. This reduction can be due to a blocked blood vessle (ischaemia) or a ruptured blood vessle (aneurism). Either way, as a result (part of) the brain is deprived of oxygen and nutrients which in turn causes neuronal degradation and cognitive decline.
