Here you can find all the entries that are tagged with Anandamide

CB1

CB1 is the main cannabinoid receptor in the brain but is also found in other tissues. CB1 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently reduces cAMP upon activation. This in turn regulates many second messenger pathways.

2AG

2AG is a major endocannabinoid produced from lipids in cellular membranes, mostly but not exclusively in response to cellular activity.

Anandamide

Anandamide was the first identified endocannabinoid, named after the Sanskrit 'ananda' for inner bliss. Anandamide is produced from lipids in cellular membranes throughout the body.

Psychosis and Schizophrenia

Schizophrenia is a chronic mental disorder that affects around 1% of the worldwide population. It causes psychotic behaviors, social and emotional disruptions and different cognitive impairments.

The causes of the disease are still not clear but studies show that both genetic and environmental factors have an effect on it.

Pain

pain is a very good target for therapeutic cannabinoids.

Obesity

Energy homeostasis (balance)  is one of the primary functions of the endocannabinoid system.

Diabetes

Diabetes has two major forms: Type 1 diabetes is an auto-immune disorder where insulin-producing β-cells in the pancreatic Islets of Langerhans are attacked by the body's immune system resulting in reduced insulin production. Type 2 diabetes results from increased tolerance of cells to insulin resulting in a reduced effect of insulin.

Alzheimer's disease

Alzheimer’s disease is a chronic neurodegenerative disease and the main cause of dementia. Main common symptoms of dementia are related with memory but other cognitive processes are affected during the development of the disease.

Addiction

Addiction is a complex physiological phenomenon that is intimately linked to the dopamine neurotransmitter system.

Virodhamine

Suspected endocannabinoid.