Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Parkinson's Disease is a degenerative disorder of the nervous system marked by accelerated degeneration of dopamine-producing neurons in the Substantia Nigra in the brain.
Typical symptoms of Parkinson's Disease , such as (intentional) tremor, rigidity and slowness of movement are mostly ascribed to degenerating Substantia Nigra neurons.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Kv3.1 is a potassium channel that functions in action potential repolarisation in fast-firing neurons. Kv3.1 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Cav3.2 is a calcium channel of the T-type that is involved in many processes in the brain and other tissues. Contrary to other calcium channels Cav3.2 is activated by relatively low/negative voltages.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Cav1 is a family of calcium channels of the L-type that are involved in many basic signalling processes in brain and muscle. Cav1's are not classic cannabinoid receptors but their activity is modulated by cannabinoids.
Submitted by heiko@ghsctradi... on Mon, 03/14/2016 - 13:14
Cav3.3 is a calcium channel of the T-type that is involved in many brain processes. Contrary to other calcium channels Cav3.3 is activated by relatively low/negative voltages.
