Diabetes

Diabetes has two major forms: Type 1 diabetes is an auto-immune disorder where insulin-producing β-cells in the pancreatic Islets of Langerhans are attacked by the body's immune system resulting in reduced insulin production. Type 2 diabetes results from increased tolerance of cells to insulin resulting in a reduced effect of insulin.

CB2

CB2 is primarily expressed in the immune cells and tissues of the body. Like CB1, CB2 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently lowers cAMP upon activation. This, in turn, regulates many second messenger pathways.

Eczema

Eczema or dermatitis is a (chronic) inflammation of the skin. Eczema is marked by itchy skin and crusty skin lesions. It is not known what exactly causes Eczema but an over-active immune system may at least be part of the cause.

COPD

COPD is a chronic lung disease. To date, no cure exists for COPD and therefore most treatments focus on reducing symptoms and suppressing discomfort.

Cancer

Cancer treatment is one of the main therapeutic applications of cannabinoids. Research has identified cannabinoids with excellent analgesic properties, cannabinoids that increase appetite and cannabinoids that reduce nausea.

Psoriasis

Psoriasis is an auto-immune disease characterized by itchy skin lesions. Psoriasis arises when the immune system mistakenly identifies skin cells as foreign matter and causes over-production of new skin cells.

AIDS

The Acquired Immune Deficiency Syndrome is caused by the Human Immunodeficiency Virus. HIV/AIDS attacks cells of the immune system making the body more susceptible to infections and tumors.