PEA

Suspected endocannabinoid.

OEA

Suspected endocannabinoid.

Obesity

Energy homeostasis (balance)  is one of the primary functions of the endocannabinoid system.

GPR119

GPR119 is involved in insulin secretion and its activation was shown to reduce food intake, suggesting a metabolic function.

2OG

Suspected endocannabinoid. Does not bind classical endocannabinoid receptors (CB1/2) but targets GPR119.  

OLDA

OLDA is an endocannabinoid that weakly binds CB1 and GPR119 but has high affinity for TRPV1. In rats, OLDA produces hyperalgesia.