Acid reflux

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Introduction

Acid reflux is a condition in which stomach acid leaks through the esophageal sphincter and irritates or corrodes the esophageal epithelium. Both esophageal epithelial cells and neurons in the esophageal myenteric plexus contain Cannabinoid receptors which appear to regulate esophageal function. Moreover, THC was found to reduce acid reflux. Still more research is required to elucidate the full involvement of the endocannabinoid system in gastro-esophageal function and the therapeutic potential of plant cannabinoids.

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