Epilepsy

cannabinoids have excellent therapeutic potential in epilepsy. In the brain, cannabinoids tend to keep neuronal activity wihtin acceptable boundaries.

Insomnia

Insomnia is a sleep disorder characterized by inability to sleep or sleeping less time than desired. The endocannabinoid system plays a role in sleep processes and medical cannabis users already reported benefits of cannabis use to sleep.

δ-opioid receptor

δ-opioid receptors are primarily sensitive to opioids and enkephalins. δ-opioid receptors are not classic Cannabinoid receptors but their activity is modulated by cannabinoids. Since cannabinoids have a physiological effect on δ-opioid receptors they are effectively Cannabinoid receptors.

Kv3.1

Kv3.1 is a potassium channel that functions in action potential repolarisation in fast-firing neurons. Kv3.1 is not a classic Cannabinoid receptor but its activity is modulated by cannabinoids.

Cav3.3

Cav3.3 is a calcium channel of the T-type that is involved in many brain processes. Contrary to other calcium channels Cav3.3 is activated by relatively low/negative voltages.

Cav3.2

Cav3.2 is a calcium channel of the T-type that is involved in many processes in the brain and other tissues. Contrary to other calcium channels Cav3.2 is activated by relatively low/negative voltages.