Nav1.5

Nav1.5 is a sodium channel that is primarily found in cardiac muscle where it is responsible for action potential generation/cardiac muscle contraction. Nav1.5 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids.

Nav1.2

Nav1.2 is a sodium channel that is involved in action potential generation in neurons and in muscle. Nav1.2 is not a classic cannabinoid receptor but its activity is modulated by cannabinoids.

TRPM8

TRPM8 is involved in sensory perception.

TRPA1

TRPA1 is best known as a sensor for environmental irritants, pain, cold and stretch.

TRPV3

TRPV3 is one of the non-GPCR-coupled cannabinoid receptors. TRPs are typically involved in pain sensation.

CBC

CBC is a cannabinoid which is reported to have anti-inflammatory, anti-viral, anti-depressant and analgesic properties.

Eczema

Eczema or dermatitis is a (chronic) inflammation of the skin. Eczema is marked by itchy skin and crusty skin lesions. It is not known what exactly causes Eczema but an over-active immune system may at least be part of the cause.

COPD

COPD is a chronic lung disease. To date, no cure exists for COPD and therefore most treatments focus on reducing symptoms and suppressing discomfort.

Depression

Both plant cannabinoids and the endocannabinoid system have been implicated as risk factors in the development of depression as well as therapeutic targets to treat depression.