CBD

CBD is the second most common cannabinoid from the plant of cannabis. In contrast to THC, CBD is not psychoactive and the reduced side effects associated to its administration makes it as important as THC regarding its therapeutic properties.

THC

D9THC is the most common cannabinoid from the cannabis plant. Better known as THC, it has psychoactive properties and its effects include altered sensory perception and reduced short-term memory. THC has also many non-psychotropic effects like reduction of pain (analgesia), stimulation of appetite and nausea reduction.

CB1

CB1 is the main cannabinoid receptor in the brain but is also found in other tissues. CB1 is a G protein-coupled receptor which inhibits adenylyl cyclase and consequently reduces cAMP upon activation. This in turn regulates many second messenger pathways.

Bladder cancer

Bladder cancers develop from the epithelial lining of the urinary bladder. cannabinoid receptors in the human bladder cancer cells could be targeted to treat the disease, but more research is needed in this field.

PEA

Suspected endocannabinoid.

OEA

Suspected endocannabinoid.

2AGE/Noladin

Suspected cannabinoid that binds to several cannabinoid receptors.

2AG

2AG is a major endocannabinoid produced from lipids in cellular membranes, mostly but not exclusively in response to cellular activity. In the brain, endocannabinoids serve mainly as negative feedback molecules (reducing presynaptic neurotransmitter release after postsynaptic activation) keeping overall brain activity in balance.

Anandamide

Anandamide was the first identified endocannabinoid, named after the Sanskrit 'ananda' for inner bliss. Anandamide is produced from lipids in cellular membranes throughout the body. In the brain, anandamide is primarily involved in negative feedback, keeping brain activity in balance. In the body, anandamide is implicated in the suppression of tumour growth, pain and vomiting and the stimulation of eating.  

Cannabiripsol

Cannabiripsol is a recently discovered cannabinoid. Whether Cannabiripsol has therapeutic properties remains to be investigated.