GlyR

Glycine receptors are sensitive to Glycine and produce a hyperpolarising current upon activation. GlyRs are not classic Cannabinoid receptora but their activity is modulated by cannabinoids.

Epilepsy

cannabinoids have excellent therapeutic potential in epilepsy. In the brain, cannabinoids tend to keep neuronal activity wihtin acceptable boundaries.

Eczema

Eczema or dermatitis is a (chronic) inflammation of the skin. Eczema is marked by itchy skin and crusty skin lesions. It is not known what exactly causes Eczema but an over-active immune system may at least be part of the cause.

Depression

Both plant cannabinoids and the endocannabinoid system have been implicated as risk factors in the development of depression as well as therapeutic targets to treat depression.

δ-opioid receptor

δ-opioid receptors are primarily sensitive to opioids and enkephalins. δ-opioid receptors are not classic Cannabinoid receptors but their activity is modulated by cannabinoids. Since cannabinoids have a physiological effect on δ-opioid receptors they are effectively Cannabinoid receptors.

TRPM8

TRPM8 is involved in sensory perception.

TRPA1

TRPA1 is best known as a sensor for environmental irritants, pain, cold and stretch.

Kv4.3

Kv4.3 is a potassium channel that is involved in the repolarisation of action potentials in cardiac muscle. Kv4.3 is not a classic Cannabinoid receptor but its activity is modulated by cannabinoids.

Kv3.1

Kv3.1 is a potassium channel that functions in action potential repolarisation in fast-firing neurons. Kv3.1 is not a classic Cannabinoid receptor but its activity is modulated by cannabinoids.

Kv1.2

Kv1.2 is a potassium channel that is responsible for maintaining resting membrane potential and regulating excitability in neurons. Kv1.2 is not a classic Cannabinoid receptor but its activity is modulated by cannabinoids.